Articles

Insulin-like growth factor-1: a possible marker for emotional and cognitive disturbances, and treatment effectiveness in major depressive disorder

Depression and cognitive dysfunction share a common neuropathological platform. Abnormal neural plasticity in the frontolimbic circuits has been linked to changes in the expression of neurotrophic factors, inc...

Authors: Oleg A. Levada and Alexandra S. Troyan

Relationship between the experience of being a bully/victim and mental health in preadolescence and adolescence: a cross-sectional study

Several studies have proven that the experiences of being bullied or bullying others are associated with poor mental health among adolescent youths. Our study aims to investigate the relationship between the e...

Authors: Sachiko Kozasa, Arata Oiji, Akio Kiyota, Tetsuji Sawa and Soo-yung Kim

Weight changes before and after lurasidone treatment: a real-world analysis using electronic health records

Severe and persistent mental illnesses, such as schizophrenia and bipolar disorder, are associated with increased risk of obesity compared to the general population. While the association of lurasidone and low...

Authors: Jonathan M. Meyer, Daisy S. Ng-Mak, Chien-Chia Chuang, Krithika Rajagopalan and Antony Loebel

Psychological and somatic distress in Chinese outpatients at general hospitals: a cross-sectional study

Our study aimed (1) to describe the proportion of psychological distress among Chinese outpatients at general hospitals, (2) to compare cognitive and behavioral characteristics of patients with different distr...

Authors: Nana Xiong, Jing Wei, Kurt Fritzsche, Rainer Leonhart, Xia Hong, Tao Li, Jing Jiang, Liming Zhu, Guoqing Tian, Xudong Zhao, Lan Zhang and Rainer Schaefert

Analysis of EEG entropy during visual evocation of emotion in schizophrenia

In this study, the international affective picture system was used to evoke emotion, and then the corresponding signals were collected. The features from different points of brainwaves, frequency, and entropy ...

Authors: Wen-Lin Chu, Min-Wei Huang, Bo-Lin Jian and Kuo-Sheng Cheng

Hospital nurses’ attitudes, negative perceptions, and negative acts regarding workplace bullying

Workplace bullying is a prevalent problem in today’s work places that has adverse effects on both bullying victims and organizations. To investigate the predictors of workplace bullying is an important task to...

Authors: Shu-Ching Ma, Hsiu-Hung Wang and Tsair-Wei Chien

An arabic translation, reliability, and validation of Patient Health Questionnaire in a Saudi sample

Psychological disorders including depression and anxiety are not rare in primary care clinics. The Patient Health Questionnaire (PHQ) is a clinical diagnostic tool that is widely utilized by primary health car...

Authors: Ahmad N. AlHadi, Deemah A. AlAteeq, Eman Al-Sharif, Hamdah M. Bawazeer, Hasan Alanazi, Abdulaziz T. AlShomrani, Raafat M. Shuqdar and Reem AlOwaybil

Effect of lamotrigine in the treatment of bipolar depression with psychotic features: a case report

Major depressive episodes with psychotic features are more common in bipolar disorder than in major depressive disorder; however, there is little information on the optimal treatment for bipolar depression wit...

Authors: Tomoko Kajiya, Hiroko Sugawara, Yusuke Kajio, Satoru Morieda, Hibiki Tanaka, Tadashi Jono, Noboru Fujise and Mamoru Hashimoto

Neurological soft signs in Tunisian patients with first-episode psychosis and relation with cannabis use

Neurological soft signs (NSS) are minor non-localizing neurological abnormalities that are conceptualized as neurodevelopmental markers that mediate the biological risk for psychosis. We aimed to explore the r...

Authors: Ahmed Mhalla, Bochra Ben Mohamed, Christoph U. Correll, Badii Amamou, Anouar Mechri and Lotfi Gaha

Leveling and abuse among patients with bipolar disorder at psychiatric outpatient departments in Ethiopia

The World Health Organization (WHO) clearly states the importance of psychological well-being in the definition of health as “a state of complete physical, mental and social well-being and not merely the absen...

Authors: Habte Belete

Islam, mental health and law: a general overview

Islam is the dominant religion in about 56 countries around the globe, and has more than 1.2 billion followers. Islam represents a holistic way of life, and according to a large proportion of its followers, th...

Authors: Georgios A. Tzeferakos and Athanasios I. Douzenis

Attempted suicide in Podgorica, Montenegro: higher rates in females and unemployed males

A change in suicide attempts is associated with comprehensive changes in mental and physical health and social environment. Attempted suicide and suicide are one of the biggest problems nowadays worldwide, not...

Authors: Lidija Injac Stevovic and Sanja Vodopic

A new technique to measure online bullying: online computerized adaptive testing

Workplace bullying has been measured in many studies to investigate mental health issues. None uses online computerized adaptive testing (CAT) with cutting points to report bully prevalence at workplace.

Authors: Shu-Ching Ma, Hsiu-Hung Wang and Tsair-Wei Chien

Amisulpride withdrawal dyskinesia: a case report

The effects of antipsychotic drug withdrawal have been inadequately studied. Case reports have described dyskinesia occurring in patients with several antipsychotics withdrawn, but studies on amisulpride withd...

Authors: Yu-Chi Lo and Ying-Chieh Peng

A case report of Lhermitte–Duclos disease revealed by psychiatric disturbances

Lhermitte–Duclos disease (LDD) is a rare cerebellar lesion characterized by a hamartomatous lesion in the posterior fossa. Mainly diagnosed by MRI, the clinical presentation is usually made of neurological sym...

Authors: Yassine Otheman, Rachid Aalouane, Chadia Aarab and Ismail Rammouz

Treatment modalities for patients with gambling disorder

Gambling disorder (GD) is defined as persistent and recurrent problematic gambling behavior leading to clinically significant impairment or distress. The prevalence of GD has been shown to be 1.2–7.1% in the g...

Authors: Sam-Wook Choi, Young-Chul Shin, Dai-Jin Kim, Jung-Seok Choi, Seohee Kim, Seung-Hyun Kim and HyunChul Youn

Bipolarity and suicidal ideation in children and adolescents: a systematic review with meta-analysis

Affective disorders in children and adolescents have received growing attention in the world scenario of mental health. Additionally, there has been an increasing prevalence of suicidal ideation in this popula...

Authors: Flórido Sampaio das Neves Peixoto, Danilo Ferreira de Sousa, Dayse Christina Rodrigues Pereira Luz, Nélio Barreto Vieira, Jucier Gonçalves Júnior, Gabriel Cabral Alencar dos Santos, Flaviane Cristine Troglio da Silva and Modesto Leite Rolim Neto

Lower suicide intention in patients with personality disorders admitted for deliberate self-poisoning than in patients with other diagnoses

People with deliberate self-poisoning and personality disorders are in increased risk for suicide. Intention and psychiatric features are important factors in a psychiatric evaluation and for planning aftercare.

Authors: T. K. Grimholt, D. Jacobsen, O. R. Haavet and Ø. Ekeberg

Is low total cholesterol levels associated with suicide attempt in depressive patients?

Patients with major depressive disorder (MDD) have a high risk of suicide. Many pathophysiological factors involved in MDD and suicide such us a low cholesterol levels have been associated with MDD and increas...

Authors: A. Messaoud, R. Mensi, A. Mrad, A. Mhalla, I. Azizi, B. Amemou, I. Trabelsi, M. H. Grissa, N. Haj Salem, A. Chadly, W. Douki, M. F. Najjar and L. Gaha

Screening of Wilson’s disease in a psychiatric population: difficulties and pitfalls. A preliminary study

Wilson’s disease (WD) is a rare autosomal-recessive, inherited disorder caused by a mutation in the copper-transporting gene ATP7B affecting the liver and nervous system. About 30% of patients with WD may initial...

Authors: Caroline Demily, François Parant, David Cheillan, Emmanuel Broussolle, Alice Pavec, Olivier Guillaud, Lioara Restier, Alain Lachaux and Muriel Bost

Erratum to: The effects of probiotics on depressive symptoms in humans: a systematic review

Authors: Caroline J. K. Wallace and Roumen Milev

Smoking and antidepressants pharmacokinetics: a systematic review

Despite an increasingly recognized relationship between depression and smoking, little is known about how smoking influences antidepressant response and treatment outcomes. The aim of this study was to systema...

Authors: Pedro Oliveira, Joana Ribeiro, Helena Donato and Nuno Madeira

Knowledge of and attitudes towards electroconvulsive therapy (ECT) among psychiatrists and family physicians in Saudi Arabia

To assess the knowledge of and attitudes towards ECT among psychiatrists and family physicians in Saudi Arabia.

Authors: Ahmad N. AlHadi, Fahad M. AlShahrani, Ali A. Alshaqrawi, Mohanned A. Sharefi and Saud M. Almousa

Insomnia severity and its relationship with demographics, pain features, anxiety, and depression in older adults with and without pain: cross-sectional population-based results from the PainS65+ cohort

Insomnia is a major cause of concern in the elderly with and without pain. This study set out to examine the insomnia and its correlates in a large sample of community adults aged ≥65 years.

Authors: Elena Dragioti, Lars-Åke Levin, Lars Bernfort, Britt Larsson and Björn Gerdle

The effects of probiotics on depressive symptoms in humans: a systematic review

Patients suffering from depression experience significant mood, anxiety, and cognitive symptoms. Currently, most antidepressants work by altering neurotransmitter activity in the brain to improve these symptom...

Authors: Caroline J. K. Wallace and Roumen Milev

Erratum to: Suicidal ideation and suicide attempts among asthma

Authors: Jae Ho Chung, Sun-Hyun Kim and Yong Won Lee

The Greek-Orthodox version of the Brief Religious Coping (B-RCOPE) instrument: psychometric properties in three samples and associations with mental disorders, suicidality, illness perceptions, and quality of life

The B-RCOPE is a brief measure assessing religious coping. We aimed to assess the psychometric properties of its Greek version in people with and without long-term conditions (LTCs). Associations between relig...

Authors: Vassiliki Paika, Elias Andreoulakis, Elisavet Ntountoulaki, Dimitra Papaioannou, Konstantinos Kotsis, Vassiliki Siafaka, Konstantinos N. Fountoulakis, Kenneth I. Pargament, Andre F. Carvalho and Thomas Hyphantis

Lifestyle factors and the metabolic syndrome in Schizophrenia: a cross-sectional study

Cardiometabolic disease is more common in patients with schizophrenia than the general population.

Authors: Adrian Heald, John Pendlebury, Simon Anderson, Vinesh Narayan, Mark Guy, Martin Gibson, Peter Haddad and Mark Livingston

Prevalence and effect of attention-deficit/hyperactivity disorder on school performance among primary school pupils in the Hohoe Municipality, Ghana

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common disorders in early childhood. However, not many studies have been conducted on the prevalence and effect of ADHD on school performance ...

Authors: Kingsley Afeti and Samuel Harrenson Nyarko

Erratum to: Agonist Opioid Treatment as historical comprehensive treatment (‘Dole & Nyswander’ methodology) is associated with better toxicology outcome than Harm Reduction Treatment

Authors: Jacopo V. Bizzarri, Valentina Casetti, Livia Sanna, Angelo Giovanni Icro Maremmani, Luca Rovai, Silvia Bacciardi, Daria Piacentino, Andreas Conca and Icro Maremmani

Erratum to: Study on the Greek demographic chart of psychic disorders

Authors: Anastasia Karkanis, John Kouros and Demy Kotta

Cardiometabolic comorbidities, readmission, and costs in schizophrenia and bipolar disorder: a real-world analysis

Serious mental illnesses are associated with increased risk of cardiometabolic comorbidities. The objective of this study was to evaluate the prevalence of cardiometabolic comorbidity and its association with ...

Authors: Christoph U. Correll, Daisy S. Ng-Mak, Dana Stafkey-Mailey, Eileen Farrelly, Krithika Rajagopalan and Antony Loebel

Erratum to: Sex differences in asking for counselling and psychological support from a therapeutic center (A.P.P.A.C.)

Authors: Anastasia Karkanis, John Kouros and Demy Kotta

HLA DRB1*03 as a possible common etiology of schizophrenia, Graves’ disease, and type 2 diabetes

Autoimmune diseases and schizophrenia share many common features. Association studies confirm a shared genetic association in the human leukocyte antigen (HLA) region between schizophrenia and most autoimmune ...

Authors: Aicha Sayeh, Cheker Ben Cheikh, Ali Mardessi, Meriem Mrad, Brahim Nsiri, Abdelaziz Oumaya and Najiba Fekih-Mrissa

Preventing involuntary admissions: special needs for distinct patient groups

Coercive measures in psychiatry are a controversial topic and raise ethical, legal and clinical issues. Involuntary admission of patients is a long-lasting problem and indicates a problematic pathway to care s...

Authors: Knut Hoffmann, I. S. Haussleiter, F. Illes, J. Jendreyschak, A. Diehl, B. Emons, C. Armgart, A. Schramm and G. Juckel

Erratum to: Family support & substance abuse during puberty

Authors: Anastasia Karkanis, John Kouros and Demy Kotta

A pilot study exploring the association of morphological changes with 5-HTTLPR polymorphism in OCD patients

Clinical and pharmacological studies of obsessive-compulsive disorder (OCD) have suggested that the serotonergic systems are involved in the pathogenesis, while structural imaging studies have found some neuro...

Authors: Shinichi Honda, Tomohiro Nakao, Hiroshi Mitsuyasu, Kayo Okada, Leo Gotoh, Mayumi Tomita, Hirokuni Sanematsu, Keitaro Murayama, Keisuke Ikari, Masumi Kuwano, Takashi Yoshiura, Hiroaki Kawasaki and Shigenobu Kanba

Antidepressive response of inpatients with major depression to adjuvant occupational therapy: a case–control study

Despite marked costs and limited evidence regarding effectiveness, occupational therapy (OT) is widely applied in psychiatric settings and financed by health insurance companies in European countries. This pil...

Authors: Marc-Andreas Edel, Brian Blackwell, Markus Schaub, Barbara Emons, Tanja Fox, Friederike Tornau, Bernward Vieten, Patrik Roser, Ida Sibylle Haussleiter and Georg Juckel

The association between altered lipid profile and suicide attempt among Tunisian patients with schizophrenia

There have been many studies on psychiatric disorders, but very little is known about the biology of suicide with schizophrenia. In the present study, we are looking for a possible connection between altered l...

Authors: Rym Mensi, Amal Messaoud, Ahmed Mhallah, Islem Azizi, Walid Haj Salah, Wahiba Douki, Mohamed Fadhel Najjar and Lotfi Gaha

Suicidal ideation and suicide attempts among asthma

The present study aimed to investigate the mental health status in patients with asthma and assess the effects of asthma on suicidal ideation and attempts using a representative sample from Korea.

Authors: Jae Ho Chung, Sun- Hyun Kim and Yong Won Lee

The newer Opioid Agonist Treatment with lower substitutive opiate doses is associated with better toxicology outcome than the older Harm Reduction Treatment

Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatme...

Authors: Jacopo V. Bizzarri, Valentina Casetti, Livia Sanna, Angelo Giovanni Icro Maremmani, Luca Rovai, Silvia Bacciardi, Daria Piacentino, Andreas Conca and Icro Maremmani

Resilience and burnout status among nurses working in oncology

This study aimed to identify the resilience and burnout status of nurses working in the field of oncology.

Authors: Sevinc Kutluturkan, Elif Sozeri, Nese Uysal and Figen Bay

Maternal bonding styles in smokers and non-smokers: a comparative study

Parental bonding has been implicated in smoking behavior, and the quality of maternal bonding (MB) has been associated with poor mental health and substance use. However, little is known about the association ...

Authors: Iren Csala, Monika Elemery, Fruzsina Martinovszky, Peter Dome, Balazs Dome, Gabor Faludi, Imola Sandor, Zsuzsa Gyorffy, Emma Birkas and Judit Lazary

Validation of the Italian version of the dissociative experience scale for adolescents and young adults

The Dissociative Experience Scale for adolescent (A-DES), a 30-item, multidimensional, self-administered questionnaire, was validated using a large sample of American young people sample. We reported the lingu...

Authors: Concetta De Pasquale, Federica Sciacca and Zira Hichy

Serum fluoxetine and norfluoxetine levels support the safety of fluoxetine in overdose

Previous literature has found fluoxetine to be relatively safe in overdose. This study hopes to examine this idea along with support from published pharmacokinetic information including serum fluoxetine and no...

Authors: Stephanie Pope and Solomon G. Zaraa

The impact of psychopathological subtypes on retention rate of patients with substance use disorder entering residential therapeutic community treatment

A specific psychopathology of addiction has been proposed and described using the self-report symptom inventory (SCL-90), leading to a 5-factor aggregation of psychological/psychiatric symptoms: ‘worthlessness...

Authors: Angelo G. I. Maremmani, Pier Paolo Pani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano and Icro Maremmani

Personality traits, gender roles and sexual behaviours of young adult males

Previous studies have shown that personality characteristics affect sexual functioning. The aim of this exploratory study was to assess and describe the relationship between global personality traits and the s...

Authors: Jacek Kurpisz, Monika Mak, Michał Lew-Starowicz, Krzysztof Nowosielski, Przemysław Bieńkowski, Robert Kowalczyk, Błażej Misiak, Dorota Frydecka and Jerzy Samochowiec

Effect of mirtazapine versus selective serotonin reuptake inhibitors on benzodiazepine use in patients with major depressive disorder: a pragmatic, multicenter, open-label, randomized, active-controlled, 24-week trial

This study aimed to evaluate whether selecting mirtazapine as the first choice for current depressive episode instead of selective serotonin reuptake inhibitors (SSRIs) reduces benzodiazepine use in patients w...

Authors: Tasuku Hashimoto, Akihiro Shiina, Tadashi Hasegawa, Hiroshi Kimura, Yasunori Oda, Tomihisa Niitsu, Masatomo Ishikawa, Masumi Tachibana, Katsumasa Muneoka, Satoshi Matsuki, Michiko Nakazato and Masaomi Iyo

Regional cortical thinning of the orbitofrontal cortex in medication-naïve female patients with major depressive disorder is not associated with MAOA-uVNTR polymorphism

Orbitofrontal cortex alterations have been suggested to underlie the impaired mood regulation in depression. MAOA-uVNTR (monoamine oxidase A-upstream variable number of tandem repeats) polymorphism has been repor...

Authors: Eunsoo Won, Sunyoung Choi, June Kang, Min-Soo Lee and Byung-Joo Ham

Analysis of personality traits and their influence on the quality of life of postmenopausal women with regard to genetic factors

Quality of life can be perceived as a subjective assessment of different aspects of human functioning. Personality is a factor which determines actions taken by individuals and their tendency to perceive reali...

Authors: Daria Schneider-Matyka, Anna Jurczak, Agnieszka Samochowiec, Beata Karakiewicz, Małgorzata Szkup, Anna Grzywacz and Elżbieta Grochans